Ketogenic science for neurology

Ketogenic Metabolism and Neurological Disease

A clinically cautious, research-led guide to ketogenic diet therapy and ketone metabolism across epilepsy, neurodegeneration, neuroimmunology, neuro-oncology, and stroke.

Current evidence

Evidence before enthusiasm

Ketogenic therapies can mean very different things depending on the condition: an established supervised therapy in selected drug-resistant epilepsy, an emerging research question in dementia and movement disorders, and an investigational metabolic strategy in brain cancer and stroke.

The pages below separate mechanisms, clinical data, uncertainty, and practical cautions so the science can be read without turning it into personal treatment advice.

Evidence review

Condition pages

Established in selected drug-resistant epilepsy

Epilepsy

The clearest neurological indication for supervised ketogenic dietary therapy.

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Emerging clinical evidence

Alzheimer's

Research asks whether ketones can support brain energy metabolism in cognitive decline.

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Emerging supportive evidence

MS

Diet research in MS is active, but ketogenic diets are not disease-modifying therapy.

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Pilot and feasibility evidence

Parkinson's

A growing research area focused on energy metabolism and non-motor symptoms.

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Adjunctive and investigational

Brain cancers

Metabolic therapy research is active, especially in glioblastoma, but survival benefit is unproven.

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Preclinical and feasibility evidence

Stroke

Ketone biology is promising in models, but stroke care is emergency medicine first.

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About this project

About

I am a neurology resident (Assistenzärztin) passionate about the science behind dietary and lifestyle interventions in chronic neurological diseases. This project is my curated map of current evidence, mechanisms, and unanswered questions in ketogenic neurology.

The aim is to make the research readable for clinicians, researchers, patients, and curious families while preserving the boundary between education and individual medical care.

Medical disclaimer

I collate current scientific evidence but do not provide individual medical advice.

The information on this website is for education and evidence curation only. It is not a diagnosis, treatment plan, nutrition prescription, or substitute for medical care. Ketogenic diets and ketone supplements can interact with medical conditions, medications, pregnancy, cancer therapy, diabetes treatment, lipid disorders, eating disorder history, kidney or liver disease, and nutritional risk. Any dietary therapy for a neurological disease should be discussed with qualified clinicians and dietitians who know the individual case.

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